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The Agilent Technologies 1260 Series HIPALS G1367E features an increased pressure range (up to 600 bar) enabling the use of today’s column technology.  The autosampler transport mechanism uses an X- Z- theta robot to optimize the positioning of the sampling arm on the well plate. Once the sampling arm is positioned over the programmed sample position, the programmed sample volume is drawn by the metering device into the sampling needle. The sampling arm then moves to the injection position where the sample is flushed onto the column.