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Category: HPLC, UPLC, & LC/MS | Subcategory: LC-MS / LC-MS/MS | Manufacturer: Agilent
Agilent 6140 Quadrupole LC/MS Mass Spectrometer With G1978B Multimode Ion Source
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The Agilent Technologies 6140 Quadrupole LC/MS Mass Spectrometer With G1978B Multimode Ion Source is a high-performance, fast-scanning model designed for high-throughput laboratories. With a scanning speed of 10,000 amu/second, it keeps pace with the Agilent 1200 Rapid Resolution LC system, the industry’s fastest liquid chromatograph.
Features:
- Orthogonal-flow sprayer with pneumatic nebulizer – enhances sensitivity across a wide range of LC conditions and reduces maintenance requirements.
- High-capacity solvent drying system – reduces chemical noise and permits the analysis of thermally-sensitive compounds through user control of gas flow rate and gas temperature.
- Dielectric platinum-plated capillary – enhances sensitivity, permits independent optimization of the spray chamber and ion optics, and allows dynamic optimization of in-source fragmentation.
- Air-cooled turbomolecular pump – provides fast startup and a small footprint, and eliminates the need for cooling water. Single, split-flow turbo pump enhances performance and increases reliability.
- Fraction collection capability – can monitor and trigger the collection of fractions based on mass, an analog signal input, or time. For mass-based determination, up to 16 m/z values can be monitored ( requires optional I/O Accessory Module).
| Specifications: | |
| Mass Range | m/z 10 – 1350 |
| Mass Accuracy | ±0.13 u within the calibrated mass range in scan mode |
| Mass Axis Stability | The mass drift does not exceed the larger absolute value of ±0.1 Da or ±100 ppm of measured mass over a 12 hour period at constant temperature ±3 degrees centrigrade |
| Scan Speed | 10,000 u/s in fast mode and 2500 u/s in normal mode |
| SIM Sensitivity | 1 pg reserpine, 100:1 RMS (20:1 peak-to-peak) ESI at 400 µ/min or APCI at 1000 µ/min Selected ion monitoring of m/z 609.3 Positive ionization |
| Scan Sensitivity | 50 pg reserpine, 100:1 RMS (20:1 peak-to-peak) ESI at 400 µ/min or APCI at 1000 µ/min Scan range m/z 100 – 650 Scan speed 2500 u/s Extracted ion at m/z 609.3 Positive ionization |
| Flow Rate, ESI | Up to 1.0 ml/min water without a flow splitter |
| Flow Rate, APCI | Up to 1.5 ml/min water without a flow splitter |
| Multisignal Acquisition | Ability to cycle through four acquisition modes on a scan-by-scan basis within a single run. Up to four analysis modes can be viewed in the software window and can be linked together to facilitate processing and analysis. Modes of operation: positive/negative polarity switching, variable fragmentor voltage selection, and concurrent SIM/scan. |
| Temperature Range | 15°C to 35°C (59°F to 95°F) |
| Relative Humidity | < 95% (non-condensing) |
| Dimensions | 15″ W x 29″ D x 26″ H (39 x 75 x 65 cm) |
| Weight | 110 lbs. (50 kg.) |
An Agilent Technologies G1978B Multimode Ion Source is installed on this unit.
| Specifications: | |
| Dimensions | 7.1″ W x 5.1″ D x 6.8″ H (18 x 13 x 17 cm) |
| Weight | 5.05 lbs. (2.29 kg.) |
Please note: system includes vacuum pump.











