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The Agilent 6420 Triple Quad LC/MS with 1260 HPLC is a highly advanced and reliable system designed for demanding applications in the fields of pharmaceuticals, environmental analysis, and forensic testing. The Agilent 6420 Triple Quad LC/MS with 1260 HPLC combines the precision and sensitivity of a triple quadrupole mass spectrometer with the robustness and flexibility of a high-performance liquid chromatography (HPLC) system.

The Agilent 6420 Triple Quad LC/MS features exceptional sensitivity and specificity, providing accurate and reliable results even at low concentrations. Its advanced ion optics and collision cell technology enable efficient ion transmission and fragmentation, resulting in highly reproducible and precise data. With a scan speed of up to 12,500 Da/s and a mass range of up to 2250 m/z, this instrument can handle complex samples with ease.

The 1260 Infinity II HPLC system integrated with the Agilent 6420 Triple Quad LC/MS provides highly accurate and reproducible separations, ensuring maximum resolution and peak shape for your compounds of interest. The system has a wide range of advanced features, including a dual-pump design, superior solvent delivery performance, and an autosampler that supports a variety of injection volumes and sample types.

The user-friendly software interface of the Agilent 6420 Triple Quad LC/MS with 1260 HPLC simplifies method development, data acquisition and analysis, and enables quick and easy creation of custom workflows. Moreover, this system offers unparalleled reliability, with minimal maintenance requirements and a long lifespan, making it a cost-effective investment for any laboratory.

Specifications:

Mass range: m/z 5 – 2,250
Polarity switching: 30 ms
Mass accuracy: 0.1 Da from 5 – 1,000 m/z 0.01% from 1,000 – 2,000 m/z 0.02% from 2,000 – 2,250 m/z
Mass stability: < 0.1 Da in 24 h
Dynamic range: > 6.0 × 106
Scan modes MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM
Maximum scan rate: 12,500 Da/s
Minimum MRM dwell time: 1 ms
MRM transitions 450 per time segment, > 40,000 ion transitions per method
Dynamic MRM transitions: 4,000 ion transitions per method
Triggered MRM transitions: Up to 10 MRM transitions (primary and secondary) for library search and compound confirmation
Collision cell ion clearance: < 1 ms
Autotune: Automated optimization of ion optics and mass axis calibration in positive and negative ion modes using a proprietary tune solution
Solvent declustering: Countercurrent gas
Detector: High-energy conversion dynode and high-gain electron multiplier horn
Vacuum system: One turbomolecular pump with one mechanical pump