Agilent G6490A Triple Quad LC/MS with 1260/1290 HPLC: G7167A MultiSampler, K1316C TCC, (2) K1312B Bin Pumps Clinical Ed., and G1379B Degasser

This Agilent G6490A Triple Quad LC/MS with 1260/1290 HPLC includes the following components:

• Agilent G6490A Triple Quad LC/MS 
• G7167A MultiSampler 
• G1316C Thermostatted Column Compartment (TCC) 
• (2) G1312B Bin Pumps Clinical Ed.
• G1379B Degasser
• Computer pre-loaded with MassHunter Software, mouse, keyboard, monitor, and cables.

This system combines unique Agilent Jet Stream technology with a hexabore capillary sampling array and dual-stage ion funnel assembly to increase ion sampling and transmission from the AJS spray plume into the 6490 ion focusing optics.

Features:

• 10 X increase in sensitivity
• Up to six orders of linear dynamic range
• Robust performance and operation
• Femtomole sensitivity for the most challenging applications

The Agilent 6490A Triple Quad LC/MS with 1260/1290 HPLC is a highly advanced and reliable system designed for demanding applications in the fields of pharmaceuticals, environmental analysis, and forensic testing. The Agilent 6490A Triple Quad LC/MS with 1260/1290 HPLC combines the precision and sensitivity of a triple quadrupole mass spectrometer with the robustness and flexibility of a high-performance liquid chromatography (HPLC) system.

The Agilent 6490A Triple Quad LC/MS features exceptional sensitivity and specificity, providing accurate and reliable results even at low concentrations. Its advanced ion optics and collision cell technology enable efficient ion transmission and fragmentation, resulting in highly reproducible and precise data. With a scan speed of up to 10,000 Da/s and a mass range of up to 1,400 amu, this instrument can handle complex samples with ease.

The 1260/1290 HPLC system integrated with the Agilent 6490A Triple Quad LC/MS provides highly accurate and reproducible separations, ensuring maximum resolution and peak shape for your compounds of interest. The system has a wide range of advanced features, including a dual-pump design, superior solvent delivery performance, and an autosampler that supports a variety of injection volumes and sample types.

The user-friendly software interface of the Agilent 6490A Triple Quad LC/MS with 1260/1290 HPLC simplifies method development, data acquisition and analysis, and enables quick and easy creation of custom workflows. Moreover, this system offers unparalleled reliability, with minimal maintenance requirements and a long lifespan, making it a cost-effective investment for any laboratory.

Specifications:

Electrospray ESI+ MS/MS sensitivity: 1 pg of res/pn on the transition m/z 609 to 195 / Signal-to-noise ratio > 60,000: 1
Electrospray ESI- MS/MS sensitivity: 1 pg of  chlo/ph/l on the transition m/z 321 to 152 / Signal-to-noise ratio > 50,000: 1
Mass Range (m/z): 5-1400 amu
Polarity switching: Switch from positive ion mode to negative ion mode in 20 ms
Mass resolution: 0.4 amu
Mass accuracy: 0.01% or 0.1 Da
Mass stability: < 0.1 u in 48 h
Dynamic range: > 6.0 x 106
Scan rate: MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM, tMRM
Minimum MRM dwell time: 1 ms
MRM transitions: 500 per second, >40,000 MRMs possible in a method
Collision cell: High-pressure, hexapole with linear acceleration collision cell
Cross-talk: None detectable
Single point of control: Single-point data system method capability with full control of Agilent 1200 Series HPLC systems and 6490 Triple Quadrupole LC/MS System
Time Programming:
Polarity change in time segment
Continuous polarity change during entire method
Scan and SIM or MRM (plus other modes of data collection)
Dynamic MRM aligns MRMs with compound retention time
Solvent divert through calibrant delivery valve
Electrospray (ESI)
Multimode source (simultaneous ESI and APCI)
Autotune: Automated optimization of ion optics and mass axis calibration with Agilent Jet stream Ion focusing technology
Solvent declustering: Agilent Jet Stream Ion Focusing Technology and Countercurrent gas
Detector: High-energy conversion dynode and high-gain electron multiplier horn
Vacuum system: Two turbomolecular pumps with two mechanical pump

Installation and Starter Kit with all appropriate filters, fittings, tubing, and gas regulators sold separately.

Includes 90 Day Warranty. 1 Year Warranty Upgrade Available.

**Please specify tray requirements at time of order (ALT will provide 1 set of 2 trays per customer specification).**

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Service Contracts, IQ/OQ, and Preventive Maintenance Contracts Available.