Category: HPLC, FPLC, & LC/MS | Subcategory: LC-MS / LC-MS/MS
Agilent  G6490A Triple Quad Mass Spectrometer
Agilent  G6490A Triple Quad Mass Spectrometer

Agilent G6490A Triple Quad Mass Spectrometer

ITEM: 32583 In Stock
Price: $79,000.00
Free 90 Day Warranty
One Year Upgrade Available
Tested & Serviced Prior to Shipping

The Agilent G6490A Triple Quad Mass Spectrometer is a highly advanced and reliable system designed for demanding applications in the fields of pharmaceuticals, environmental analysis, and forensic testing.

The Agilent G6490A Triple Quad Mass Spectrometer features exceptional sensitivity and specificity, providing accurate and reliable results even at low concentrations. Its advanced ion optics and collision cell technology enable efficient ion transmission and fragmentation, resulting in highly reproducible and precise data. With a scan speed of up to 10,000 Da/s and a mass range of up to 1,400 amu, this instrument can handle complex samples with ease.

The user-friendly software interface of the Agilent G6490A Triple Quad Mass Spectrometer simplifies method development, data acquisition and analysis, and enables quick and easy creation of custom workflows. Moreover, this system offers unparalleled reliability, with minimal maintenance requirements and a long lifespan, making it a cost-effective investment for any laboratory.

This system combines unique Agilent Jet Stream technology with a hexabore capillary sampling array and dual-stage ion funnel assembly to increase ion sampling and transmission from the AJS spray plume into the 6490 ion focusing optics.


  • 10 X increase in sensitivity
  • Up to six orders of linear dynamic range
  • Robust performance and operation
  • Femtomole sensitivity for the most challenging applications


Electrospray ESI+ MS/MS sensitivity: 1 pg of res/pn on the transition m/z 609 to 195 / Signal-to-noise ratio > 60,000: 1
Electrospray ESI- MS/MS sensitivity: 1 pg of  chlo/ph/l on the transition m/z 321 to 152 / Signal-to-noise ratio > 50,000: 1
Mass Range (m/z): 5-1400 amu
Polarity switching: Switch from positive ion mode to negative ion mode in 20 ms
Mass resolution: 0.4 amu
Mass accuracy: 0.01% or 0.1 Da
Mass stability: < 0.1 u in 48 h
Dynamic range: > 6.0 x 106
Scan rate: MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM, tMRM
Minimum MRM dwell time: 1 ms
MRM transitions: 500 per second, >40,000 MRMs possible in a method
Collision cell: High-pressure, hexapole with linear acceleration collision cell
Cross-talk: None detectable
Time Programming:
Polarity change in time segment
Continuous polarity change during entire method
Scan and SIM or MRM (plus other modes of data collection)
Dynamic MRM aligns MRMs with compound retention time
Solvent divert through calibrant delivery valve
Electrospray (ESI)
Multimode source (simultaneous ESI and APCI)
Autotune: Automated optimization of ion optics and mass axis calibration with Agilent Jet stream Ion focusing technology
Solvent declustering: Agilent Jet Stream Ion Focusing Technology and Countercurrent gas
Detector: High-energy conversion dynode and high-gain electron multiplier horn
Vacuum system: Two turbomolecular pumps with two mechanical pump

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