Applied Biosystems API 4000 LC-MS/MS System

The industry-standard Applied Biosystems API 4000 LC/MS/MS System brings high-performance quantitation and identification to every phase of the pharmaceutical development process, from discovery to clinical research trials.

The Applied Biosystems API 4000 LC-MS/MS System offers proven curtain gas interface technology and improved gas dynamics to reduce maintenance and increase uptime. The system also provides enhanced high flow-rate performance, reduced ionization suppression, self-cleaning probe design, and a reliable interface for accelerated productivity and high throughput.

Features: 

• Low Limits of Detection – The high sensitivity of the API 4000 system ensures low detection limits. Efficient ionization and superior ion sampling of the interface result in excellent sensitivity.
• Flexible Options Increase Throughput – Easy-to-use TURBO V source allows you to quantitate over a wide range of flow rates and to change rapidly between atmospheric pressure chemical ionization (APCI) and TurboIonSpray® probes. The optional DuoSpray ion source accelerates method development and increases both throughput and data quality. An additional option for atmospheric pressure photo-ionization, the PhotoSpray source, expands the range of compounds you can analyze.
• Automated Data Acquisition – Innovative software applications enable automated MS to MS/MS acquisition, allowing you to extract the maximum amount of information from a single LC/MS run.
• Rugged, Reliable, and Easy to Use – The superior ionization efficiency, enhanced robustness, and ease of use of the innovative TURBO V source, combined with the patented LINAC® collision cell, delivers high performance and high productivity with greater confidence in your results.
• Fast, Secure Access to Information for DMPK Studies – Integration with Analyst software’s powerful data acquisition and processing capabilities provides fast and secure access to the information you need for DMPK studies.

Specifications:

Gas Supplies: 60 psi high purity nitrogen, 100 psi zero grade air, 60 psi filtered, dry air
Mass Accuracy: 0.01% over the entire mass range
Dynamic Range: 1 cps to 4 x 106 cps (pulse counting)
Mass Range: m/z 5-3,000
Dimensions: 53″ W x 20″ D x 21.5″ H (130 x 50 x 52 cm)
Weight: 136 kg (299.2 lb)
Computer Requirements: PC with Windows 2000/XP operating system, CD-ROMCVC RW (CD RW capable), Memory;1 GB RAM, CPU3.2 GHz, Hard Disk 200GB; Display 19″ Viewable Color monitor recommended; Power, Voltage 2, separate 207 V minimum to 242 V.

Please note: system includes vacuum pump.