Category: Microplate Readers | Subcategory: Multimode Readers

Beckman Coulter DTX 880 Multimode Detector

Beckman Coulter DTX 880 Multimode Detector Image

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Beckman Coulter DTX 880 Multimode Detector ImageBeckman Coulter DTX 880 Multimode Detector ImageBeckman Coulter DTX 880 Multimode Detector ImageBeckman Coulter DTX 880 Multimode Detector Image

The Beckman Coulter DTX 880 Multimode Detector is capable of performing fluorescence, luminescence and absorbance measurements and can operate as standalone instruments or can be integrated seamlessly with Biomek Laboratory Automation Workstations. Ideal for a broad range of Systems Biology applications, including drug discovery, genomics, proteomics and cell-based research.

The DTX 880 is a spectrophotometer for the UV-Visible wavelength range that provides the operator a great deal of flexibility for sample analysis. Accepting a range of microplates from 6- to 384-well plates means operators have a fair amount of flexibility in assay development. Increasing flexibility in analysis are the seven detection modes provided by the DTX 880. Included are seven detection modes ranging from fluorescence, glow luminescence, and absorbance. Fluorescence modes include fluorescence intensity (top and bottom reads), time-resolved fluorescence, and fluorescence polarization. Absorbance modes include detection for both UV and visible spectra. Reading modes can be programmed for endpoint, kinetic, multiple wavelengths, linear scan and area scan. This variety of reading mode options is what makes this multimode spectrophotometer such a flexible option for research laboratories.

With this instrument, laboratories are given two viable options for fast and sensitive readings. This multimode detector is capable of both stand-alone operation and integration with robotic systems. The integration of such systems is facilitated by a plate access door that is wide enough to allow for versatile positioning of robotic ports. Regardless of integration, speed is provided with results given in times anywhere between mere seconds for Fluorescence Intensity (Top Read) and a few minutes for Time-Resolved Fluorescence. Speed does not come at a loss in sensitivity, which is completely adjustable by the user who has the ability to adjust the read heights of the detector. All aspects of detection and programming are easily controlled via computer-based software designed for the instrument.

Fluorescence 230–750 nm and Luminescence 400–750 nm Plate reader for 96 or 384 plates The DTX Multimode plate readers are ideal for use in applications such as drug discovery, genomics, proteomics, and cell-based research. These instruments can operate as stand-alone devices or can be integrated into Biomek* laboratory automation workstations. The unique optics design ensures precise performance and sensitivity across all detection modes. Integration with automated liquid handling systems is facilitated by a choice of plate loading options, which include an extra-wide plate access door, and the ability to accept plates in portrait or landscape formats. The DTX 880 features seven modes of detection: Fluorescence intensity-top read and fluorescence intensity-bottom read, time-resolved fluorescence, fluorescence polarization, absorbance-UV, absorbance-visible, glow luminescence, and temperature control for 6-well to 384-well plates. The instrument is also capable of linear and orbital shaking. Programmable endpoint, kinetic, multiple wavelength, linear scan, and area scan measurement types are available. Easily accessible 6-position filter slides allow wavelength selection from 230–750nm.

Light SourceHigh Power LEDs + Deuterium Lamp
DetectorsSilicon Photodiode + PMT
Filters2 EX + 1 EM Filter Slides (6 filter capacity)
Plate Formats6- to 384-well
ShakingLinear + Orbital (3 speeds)
Temperature ControlAmbient +4°C to 45°C
Power/Voltage100-240 VAC; 50/60 Hz
Dimensions15.35" W x 22.83" D x 9.44" H (39 × 58 x 24 cm)
Weight55.12 lbs. (25 kg)
Fluorescence Intensity - Top Read 
Wavelength Range230-750 nm
Detection Limit – 96-well plate1.5 fmol fluorescein
Detection Limit – 384-well plate1.5 fmol fluorescein
Linear Dynamic Range5 decades
Read Time18 sec / 96-well
Fluorescence Intensity-Bottom Read 
Wavelength Range300-650 nm
Detection Limit – 96-well plate50 fmol fluorescein
Detection Limit – 384-well plate25 fmol fluorescein
Time-Resolved Fluorescence 
Wavelength Range340-750 nm
Detection Limit – 96-well plate50 amol Europium
Detection Limit – 384-well plate30 amol Europium
Read Time (1 sec integration)180 sec / 96-well
Fluorescence Polarization 
Wavelength Range300-750 nm
Detection Limit – 96-well plate5 mP at 10 nM Fluorescein
Detection Limit – 384-well plate5 mP at 10 nM Fluorescein
Read Time38 sec / 96-well
Luminescence (Glow) 
Wavelength Range400-750 nm
Detection Limit – 96-well plate2 fmol ATP 2 fmol ATP
Linear Dynamic Range5 decades 5 decades
Read Time18 sec / 96-well
Wavelength Range230-650 nm
Indication Range0-3.5 OD
AccuracyLess than ± 1 % ± 10 m OD at 2 OD
ReproducibilityLess than ± 0.5 % and ± 0.005 OD at 2 OD
Read Time18 sec / 96-well

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