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The Malvern Panalytical NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.

The NS300 allows rapid analysis of the size distribution and concentration of all types of nanoparticles from 0.01 - 1 µm* in diameter, depending on the instrument configuration and sample type.

With the ability to be supplied with interchangeable laser modules and the introduction of a motorized filter wheel means different fluorescent labels can be analyzed. Sample temperature is fully programmable through the Nanoparticle Tracking Analysis (NTA) software.

This versatile instrument offers the major benefit of minimum user set-up, enhanced concentration measurements via advanced algorithms and fluorescence detection capability providing truly holistic analysis. The fully software-controlled filter wheel means automated analysis of fluorescent markers can be performed while walk-away NTA measurements for multiple samples can be performed when used with the Sample Assistant accessory.

Concentration values are linear over a wide range of sample dilutions and show excellent alignment with calculated concentration values. Example data obtained on NS300 using NIST-traceable 150 nm latex particles.

The NanoSight Syringe Pump enables analysis in constant flow (with 1 mL syringes) for improved sample statistics and measurement of photo-bleaching fluorescent samples.

Features:

Assured and visual

Measure over 1000 particles in just 60 seconds

Particle-by-particle analysis for high resolution size and concentration

Visual validation of results gives extra confidence

Camera operates at 30 frames per second (fps), capturing a video of particles in Brownian motion

User-friendly software with easy set up of SOPs for routine use

Minimal sample preparation

On board temperature control

Choice of laser wavelengths

Complies with Industry Standards ISO 19430:2016 and ASTM E 2834:2012

Add up to 5 additional filters in a motorized wheel for flexible fluorescence detection capability

 

The software tracks many particles individually and using the Stokes-Einstein equation calculates their hydrodynamic diameters. The measurement is controlled via Standard Operating Procedures which are set with a user-friendly software interface.

Specifications:
Particle Size	10nm - 1000nm (Sample and system configuration dependent)
Concentration Range	106 to 109 particles per mL
Minimum Sample Volume	250 μL
Stage	Fixed stage
Focus	Computer controlled motorized focus
Fluorescence	Motorized filter wheel with choice of up to 5 filters
Conforms to	Product laser class 3R (EC/EN60825) EMC Directive: 2014/30/EU {EN 61326-1: 2013} Low Voltage Directive: 2014/35/EU {EN 61010-1: 2010} RoHS Directive: 2011/65/EU & (EU) 2015/863 (EN63000: 2018)
Camera	High sensitivity sCMOS (USB-3)
Wavelength	Beam wavelength (maximum power output): 405 nm, max power <70 mW (violet) 488 nm, max power <55 mW (blue) 532 nm, max power <60 mW (green) 642 nm, max power <50 mW (red)
Temperature Control Range	5°C below ambient to 50°C, Automatic readout
Dimensions	9.84" W x 15.75" D x 15.75" H (25 x 40 x 40 cm)
Weight	27.9 lbs. (13 kg)
Power	110-240V, 50-60Hz, 4.0A
Ambient Conditions	Up to 80% rH at 31°C then decreasing linearly to 50% at 40°C