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The Malvern Instruments Zetasizer Nano ZS, ZEN3600 provides dynamic light scattering (DLS) for the measurement of the size of colloids, nanoparticles and molecules, without requiring agitation to make the sample suitable for analysis. From the size, an estimate of the molecular weight can be made, which has the benefit of being faster to confirm oligomeric state than size exclusion chromatography (SEC).

Features:

• Little or no dilution required to simplify sample preparation
  
• Wide range of sample suitability from nanoparticles to emulsions and macromolecules
  
• MPT-2 Autotitrator to automate pH and ionic concentration trends, improving productivity
  
• Elimination of cross-contamination using disposable cells to improve accuracy
  
• Data assessment using quality report and ‘Expert advice’ system
  
• Can be used as a chromatography detector for on-line size measurement.
  
• NIBS optics ensures exceptional performance
  
• Automation of temperature trends
  

Specifications:

Parameters measured
Temperature control range: 0ºC to 90ºC +/- 0.1ºC
Condensation control: Purge using dry air
Standard laser: 4mW, 633nm
Correlator:  25ns to 8000s, max 4000 channels

Size
Absolute sensitivity (Toluene kcps): 150 
Range (Maximum diameter): 0.3nm - 10 microns
Min sample volume: 12μL 
Min concentration, protein: 0.1mg/mL 15kDa protein 
Min concentration, forward angle: 10mg/mL 66kDa protein
Max concentration: 40% w/v
Measurement angles: 13° + 173° 
Analysis algorithms: General purpose NNLS, multiple
narrow modes, protein

Zeta potential
Sensitivity: 10mg/mL 66kDa protein 
Zeta potential range: > +/-500mV 
Mobility range: > +/- 20 μ.cm/V.s  
Maximum sample concentration: 40% w/v 
Minimum sample volume (using diffusion barrier): 20μL 
Maximum sample conductivity: 200mS/cm 200mS/cm
Signal processing: M3-PALS 

Molecular weight
Molecular weight range (estimated from DLS): <1000Da - 2 x 107
Molecular weight range (Debye plot): <1000Da - 2 x 107 Da
Dimensions: 12.6" W x 23.6" D x 10.2" H (32 x 60 x 26 cm)
Weight: 41.8 lbs (19 kg)