Cell Sorter

Cell sorters are specialized flow cytometers that enable researchers to isolate and purify individual cells based on their unique characteristics. These sophisticated instruments use lasers to illuminate cells labeled with fluorescent markers, measuring light scatter and fluorescence intensity to identify specific cell populations. Based on these measurements, the cell sorter uses a variety of techniques, including droplet-based sorting and microfluidic chip sorting, to physically separate target cells from the heterogeneous sample. This facilitates downstream applications like single-cell genomics, cell cloning, and cell-based assays. Leading manufacturers of cell sorters include BD Biosciences with their FACSAria and FACSJazz series, Bio-Rad with the S3e Cell Sorter, and Sony with the MA900 Multi-Application Cell Sorter. Cell sorting supports diverse... + More

Cell sorters are specialized flow cytometers that enable researchers to isolate and purify individual cells based on their unique characteristics. These sophisticated instruments use lasers to illuminate cells labeled with fluorescent markers, measuring light scatter and fluorescence intensity to identify specific cell populations. Based on these measurements, the cell sorter uses a variety of techniques, including droplet-based sorting and microfluidic chip sorting, to physically separate target cells from the heterogeneous sample. This facilitates downstream applications like single-cell genomics, cell cloning, and cell-based assays. Leading manufacturers of cell sorters include BD Biosciences with their FACSAria and FACSJazz series, Bio-Rad with the S3e Cell Sorter, and Sony with the MA900 Multi-Application Cell Sorter. Cell sorting supports diverse workflows in fields like immunology, cancer research, and stem cell biology. Researchers can isolate specific immune cell subsets for functional studies, purify circulating tumor cells for diagnostics, or separate stem cells for regenerative medicine applications. Common techniques compatible with cell sorting include fluorescence-activated cell sorting (FACS), cell cycle analysis, and apoptosis assays. By providing highly pure cell populations, cell sorters contribute significantly to advancements in basic research and clinical applications. - Less