GC-MS

Gas chromatography-mass spectrometry (GC-MS) systems combine the separation power of gas chromatography with the qualitative and quantitative capabilities of mass spectrometry. This powerful analytical technique separates volatile and semi-volatile compounds in a sample, then identifies and quantifies them based on their mass-to-charge ratio. GC-MS instruments from leading manufacturers like Agilent, Thermo Fisher Scientific, Shimadzu, and PerkinElmer utilize advanced technologies such as quadrupole, ion trap, and time-of-flight mass analyzers to deliver precise results. These systems support diverse workflows including environmental monitoring, food safety testing, forensic analysis, and metabolomics research, enabling scientists to identify unknown compounds, confirm the presence of specific analytes, and determine the concentration of various substances within complex mixtures. GC-MS workflows often involve sample... + More

Gas chromatography-mass spectrometry (GC-MS) systems combine the separation power of gas chromatography with the qualitative and quantitative capabilities of mass spectrometry. This powerful analytical technique separates volatile and semi-volatile compounds in a sample, then identifies and quantifies them based on their mass-to-charge ratio. GC-MS instruments from leading manufacturers like Agilent, Thermo Fisher Scientific, Shimadzu, and PerkinElmer utilize advanced technologies such as quadrupole, ion trap, and time-of-flight mass analyzers to deliver precise results. These systems support diverse workflows including environmental monitoring, food safety testing, forensic analysis, and metabolomics research, enabling scientists to identify unknown compounds, confirm the presence of specific analytes, and determine the concentration of various substances within complex mixtures. GC-MS workflows often involve sample preparation techniques like liquid-liquid extraction or solid-phase microextraction to isolate target compounds before analysis. The GC separates the components of the sample based on their boiling points and interaction with the stationary phase of the column. The separated compounds then enter the mass spectrometer, where they are ionized and fragmented. The resulting ions are detected and analyzed, generating a mass spectrum that serves as a unique fingerprint for each compound. This information allows researchers to identify and quantify the components of the sample, providing valuable insights into its composition and properties. Popular GC-MS models like the Agilent 7890B/5977B and the Thermo Scientific TSQ 9000 are widely used in various scientific disciplines, offering robust performance and reliability for demanding applications. - Less