Spectropolarimeter

Spectropolarimeters, also known as circular dichroism (CD) spectrometers, are analytical instruments that measure the optical rotation and differential absorption of left- and right-circularly polarized light as it passes through a sample. This technique is particularly valuable for studying chiral molecules, since the degree and direction of optical rotation can reveal information about a compound's stereochemistry, secondary structure, and conformational changes. Spectropolarimeters typically illuminate a sample with polarized light across a range of wavelengths and record the resulting ellipticity or rotation, generating a spectrum that reflects the sample's structural characteristics. These instruments are especially important in structural biology and pharmaceutical research, where they are used to assess the secondary structure of proteins and peptides, monitor protein... + More

Spectropolarimeters, also known as circular dichroism (CD) spectrometers, are analytical instruments that measure the optical rotation and differential absorption of left- and right-circularly polarized light as it passes through a sample. This technique is particularly valuable for studying chiral molecules, since the degree and direction of optical rotation can reveal information about a compound's stereochemistry, secondary structure, and conformational changes. Spectropolarimeters typically illuminate a sample with polarized light across a range of wavelengths and record the resulting ellipticity or rotation, generating a spectrum that reflects the sample's structural characteristics. These instruments are especially important in structural biology and pharmaceutical research, where they are used to assess the secondary structure of proteins and peptides, monitor protein folding and stability, and confirm the identity and purity of chiral pharmaceutical compounds. Spectropolarimeters also find use in polymer science and materials characterization for studying optically active compounds. Manufacturers such as JASCO, Applied Photophysics, and Olis produce spectropolarimeters and CD spectrometers ranging from basic research-grade instruments to high-throughput systems, supporting applications from academic structural biology labs to pharmaceutical quality control and biologics characterization. ALT carries a wide selection of pre-owned, refurbished spectropolarimeters. Every unit includes a standard 90-day warranty, with the option to upgrade to a three-year warranty, plus ALT's lifetime support for as long as you own the equipment. Refurbished spectropolarimeters from ALT typically cost 50%-80% less than buying new, making it easier for labs to get the equipment they need without straining their budget. - Less